In Reckoning, we learn Samantha was devoured by the Forsaken, or at least that's what he says happened. Here's the quote: "Is that computer back to badger me? She talks like that woman I devoured." Anyway, IF Zykov's not bullshitting, and he actually devoured her, then that's actually confirmation she's coming back very soon.
Why? Because in Cold War Sparagmos (an Old One) makes a prophecy that once Zykov is dead, all devoured by him will be reborn. Here's an excerpt from his prophecy:
"The Devoured shall be reborn.
Their scattered ashes shall be reformed.
The Forsaken’s torment will be undone,
When the Old Ones reign once more."
So everyone devoured by him, doesn't matter if they were human, or Elder God, will start to come back soon enough, since he's finally out of the picture. Just wanted to share for my Maxisheads in the crowd <333