I’m running 1.55 V with very tight memory timings. The only concern I had before was memory cooling, since I was just placing a fan on top of the CPU block.
I’ve now switched to using an older CPU fan mounted with tall motherboard standoffs. By the way you can buy the standoffs separately without purchasing the whole bench.
After 20 loops in Port Royal, memory temperatures don’t exceed 40 °C, compared to 48 °C at 1.5 V with the same settings.